Colca, J.R., McDonald, W.G., McCommis, K.S., Finck, B.N. (2017) Treating Fatty Liver Disease by Modulating Mitochondrial Pyruvate Metabolism.  Hepatology Comm. 1:193-197.

McCommiss, K.S., Hodges, W.T., Brunt, E.M., Nalbantoglu, I., MDonald, W.G., Holley, C., Fujiwara, H., Schaffer, J.E., Colca, J.R., Finck, B.N. (2016) Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis. Hepatology. Doi: 101002/hep.29025.

Colca, J.R. (2015) The TZD insulin sensitizer clue provides a new route into diabetes drug discovery.  Expert Opin Drug Discov. 10(12):1259-70.

McCommis, K.S., Chen, Z., Fu, X., McDonald, W.G., Colca, J.R., Kletzien, R.F., Burgess, S.C., Finck, B.N. Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling. Cell Metab. (2015); 22:682-94.

Shah R.C., Matthews D.C., Andrews R.D., Capuano A.W., Fleischman, VanderLugt J.T., Colca J.R. (2014) An Evaluation of MSDC-0160, a Prototype mTOT Modulating Insulin Sensitizer, in Patients with Mild Alzheimer’s Disease. Current Alzheimer Research 11:564-573.

Fukunaga T., Zou W.,  Rohatgi  N.,  Colca J.R.,  Teitelbaum, S.L. (2014) An insulin-sensitizing thiazolidinedione, which minimally activates PPARγ, does not cause bone loss. J Bone Miner Res. doi: 10.1002/jbmr.2364.

Colca, J.R., McDonald, W.G., Kletzien, R.F. (2014) Mitochondrial target of thiazolidinediones. Diabetes, Obesity, and Metabolism 16(11):1048-54.

Colca, J.R. VanderLugt, J.T., Adams, W.J., Shashlo, A., McDonald, W.G., Liang, J., Zhou R., Orloff, D.G. (2013) Clinical proof of concept with MSDC-0160, a prototype mTOT modulating insulin sensitizer. Clinical Pharmacology and Therapeutics, 93:  352-359.

Colca, J.R., McDonald, W.G., Cavey, G.S., Cole S.L., Holewa, D.D., A.S. Brightwell-Conrad, A.S., Wilson, J., Coulter, K., Kilkuskie, P., Gracheva, E., Karr, R., Wiley, S., Divakaruni, A.S., Murphy, A., Finck, B.N., Kletzien, R.F. (2013) Identification of a Mitochondrial Target of Thiazolidinedione Insulin Sensitizers (mTOT)-relationship to newly identified mitochondrial pyruvate carrier proteins. PLoS ONE 8:e61551:1-10.

Colca J.R., Tanis S.P., McDonald W.G., Kletzien R.F. (2013) Insulin sensitizers in 2013: new insights for the development of novel therapeutic agents to treat metabolic diseases. Exp. Opin. Invest. Drugs 23: 1-7.

Divakaruni, A.S., Wiley, S.E., Rogers, G.W., Andreyev, A.Y., Petrosyan, S., Loviscach, M., Wall, E.A., Yadava, N., Heuck, A.P., Ferrick, D.A., Henry, R.R., McDonald, W.G., Colca, J.R., Simon, M.I., Ciaraldi, T.P., Murphy, A.N. (2013) Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. PNAS 110: 5422 – 5427.

Rohatgi, N., Aly, H., Marshall, C.A., McDonald, W.G., Kletzien, R.F., Colca, J.R., McDaniel, M.L. (2013). Novel Insulin Sensitizer Modulates Nutrient Sensitizing Pathways and Maintains b-cell Phenotype in Human Islets. PloS ONE:8 e62012: 1-13.

Chen, Z., Vigueira, P.A., Chambers, K.T., Hall, A.M., Mitra, M.S., Qi, N., McDonald, W.G., Colca, J.R., Kletzien, R.F., Finck, B.N.  (2012) Insulin Resistance and Metabolic Derangements in Obese Mice Are Ameliorated by a Novel Peroxisome Proliferator-activated Receptor-sparing Thiazolidinedione. J. Biol. Chem., 287: 23537-23548.